Top 10 Weird Diseases That Will Leave You Shocked

Top 10 Weird Diseases in the World That Will Leave You Shocked

Diseases that are rare usually have no cure, which is another reason why they are so bizarre and scary besides the fact that they are already atypical. Here’s a list of word’s top 10 weird rare diseases.

Weird Disease in the World #1: Riley-Day Syndrome

Riley-Day Syndrome:

Riley-Day syndrome, known as Familial dysautonomia or hereditary sensory neuropathy type 1 (HSN), is a condition of rare genetic mutations that affect the autonomic nervous system connecting the brain and spinal cord to muscles and cells that detect sensation sensations, such as touch, smell, and pain.The ability to feel pain and temperature is very disturbed, sometimes to the point where the individual really does not experience pain at all.

To really show signs of having a condition, however, the relevant gene must be passed down by both parents. This condition is also accompanied by frequent vomiting and difficulty swallowing.

Because HSN causes loss of pain sensation, it is no longer a new item for sufferers to suffer from random fractures and even necrosis, which results in the death of body tissues. People with HSN can even sever their limbs or bite their tongue without feeling the slightest pain. Insensitivity to aches and pains can be life threatening in many situations, and because injuries and injuries may continue to be left untreated, boils and infections are common side effects.

Weird Disease in the World #2: Hypertrichosis


Another horror movie theme that “inspires” a description of this rare disease. Known as cognital hypertrichosis lanuginose, those born with this congenital condition have too much and too much hair growth due to genetic mutations, thus covering the body, including the face.

This is the reason why hypertrichosis is also commonly referred to as the “werewolf” syndrome – without creepy canines and sharp claws.

Weird Disease in the World #3: Exploding head syndrome

A loud voice wakes you up at night or surprises you until you jump. Though there is not a single thing that causes noise. The loud voice came from inside your head.Exploding head syndrome

Exploding Head Syndrome sounds like a scenario from a horror film, but this is actually a serious medical condition that affects thousands of people around the world. Symptoms of this disease are sleep that is disturbed by flashes of bright light, shortness of breath, increased heart rate, accompanied by sounds that sound like a bomb exploding, gun shots, a cymbal impact, or other versions of loud noises in one’s head while trying to sleep. There are no symptoms of pain, swelling or other physical problems.

When the head “explodes”, the situation is usually described as a brain shutdown process , similar to a dead computer. When the brain goes to sleep, the brain will “die” gradually, starting from the motor, hearing, and nerve aspects, which are followed by visuals – but then something is wrong in the process sequence. Unfortunately, the drugs available at this time were only able to reduce the volume of the explosion but did not actually stop the sound.

Weird Disease in the World #4: Alien Hand: Hands

Alien HandThe Alien Hand Syndrome is a strange disease that makes the owner of the body completely unable to control the movements of his own hands. As if both hands have life and a way of thought that is separated from the body.

Many researchers believe that it could be a side effect of surgery relating to the brain. They found that the left and right brain had the ability to move independently of independent will. Sometimes, this syndrome can arise as a side effect that is rare due to brain injury.

The Alien Hand Syndrome has no cure, but it is advised to always hold something in hands to make them stop moving for a while. A study published in the journal Neurologist reports that Botox injections can help manage this syndrome.

Weird Disease in the World #5: Persistent sexual arousal syndrome

Persistent sexual arousal syndrome

Passion and seconds to climax will usually only be felt during sex or masturbation. However, a handful of people can almost at any time be on the verge of orgasm  during daily activities. For example when crossing a road or even waiting for a public bus. Even though. they do not experience or receive sexual stimulation in the lightest.

This continually stimulated condition is called Persistent Sexual Arousal Syndrome (PSAS). PSAS can attack anyone regardless of age, gender, or sexual orientation. However, the cause is unknown until now.

Some scientists believe that nerve hypersensitivity in the genital organs can be one of the causes. Others suspect that narrowing of venous veins in the pelvis to hormonal disorders is the cause.

This condition can also be caused by side effects from anti-bald medication, although some other cases occur without known cause. Treatment options include general hair removal methods, although even regular waxing and laser treatments do not provide long-lasting results.

Weird Disease in the World #6: Stone Man’s disease

Stone Man's disease

Medically known as Ossificans Progressiva Fibrodysplasia (FOP), Stone Man’s disease is one of the rarest, most painful, and most disabling genetic conditions. Stone Man’s disease causes new bone growth to appear replacing muscles, tendons, ligaments, and other connective tissue that should not be overgrown with bone.

This strange disease is caused by genetic mutations in the body’s immune system to repair injuries. After injury, new bones will develop throughout the joint, limiting movement and forming a second skeleton. This condition makes the sufferer like a living mannequin statue that moves stiffly. Trauma and even the slightest injury, even injection marks, can cause bones to start growing.

Unfortunately, there is no effective treatment for this condition other than taking a general pain reliever. FOP occurs in one in two million people, but there are only 800 cases officially registered in the world.

Weird Disease in the World #7: Foreign Accent Syndrome:

Accents can reveal a lot of information about a person’s origin, and many people have tried to speak a foreign language other than their own mother tongue. However, some people can develop a condition that causes them to be suddenly fluent in foreign languages and uncontrollable, even if they have never studied or visited the area of origin of the language before. Often, several different types of accents can “come out” at different times, or can be mixed up at one time.foreign_accent_syndrome

Individuals with this condition not only change their accent and tone of voice, but also change the placement of the tongue when speaking. This rare, rare disease usually appears as a side effect after a stroke, severe migraine, or other brain injury. 

Weird Disease in the World #8: Progeria

progeriaGenerally, symptoms of aging will begin to appear in middle age. But for children who have Progeria or Hutchinson-Gilford Progeria Syndrome 3, their physical appearance even looks like an 80-year-old elderly even though the actual age has not been two years. Progeria is caused by genetic defects.

Even though they are mentally correct, they are still underage, physical children with progression physically will grow older like elderly people. Starting from hair loss and thinning, graying, sagging skin and wrinkles here and there, suffering from joint pain, to bone loss.

Progreria is a rare life-threatening condition. There are only 48 children worldwide who have managed to grow up with this condition. On average, children born with progeria will not survive past the age of 13. 

Progeria is deadly because many of these children also develop diseases that are usually associated with old age, such as heart disease and arthritis . They experience acute arterial hardening ( arteriosclerosis ) which begins in childhood, which triggers a heart attack or stroke at a very young age.

Weird Disease in the World #9: Xeroderma Pigmentosum

Humans need sunlight to get vitamin D, but about 1 in 1 million people who have xeroderma pigmentosum (XP) and are very sensitive to UV light. They must be completely protected from the sun, or will experience extreme sunburn and severe skin damage.

Xeroderma pigmentosum (XP) is a subtype of a disorder known as porphyria . This condition is caused by a mutation of a rare enzyme that causes the skin to not heal itself once damaged by exposure to UV radiation.

Symptoms usually first appear in early childhood, characterized by severe blistered skin after only a few minutes of exposure. The eyes also become red, blurred, and irritated from UV exposure.

People with XP are at very high risk of developing skin cancer. Nearly half of all children who have XP will develop certain types of skin cancer at the age of 10. It is estimated that only one in 250,000 people in Europe and the United States has XP. Although there are several treatments available, the best prevention of severe skin damage is just staying in the dark and away from the sun.

Weird Disease in the World #10: Cotard’s delusion

Cotard’s delusion, aka Walking Corpse Syndrome, is a rare mental disorder in which a person believes wholeheartedly that he is a zombie. They believe they are dead but half alive for reasons that don’t make sense if we hear it. For example, he felt all the blood in his body was drained, his spirit was taken by the devil, or all his organs had been stripped off.

Some people who have this syndrome may also claim that he can smell his own flesh to rot or feel maggots crawling on his skin. Some others believe that they cannot die (because they are dead, according to them).

Sufferers tend not to eat or take a bath, and often spend time in the cemetery on the pretext of wanting to mingle with their own “people”.

This condition is most common among schizophrenics and people who have suffered severe head trauma. People who  lack chronic sleep or suffer from psychosis after using amphetamine or cocaine often show symptoms of Cotard syndrome.

Cotard’s delusion is thought to occur due to a disturbance in the area of the brain that is responsible for recognizing and connecting emotions with the face, including their own faces. This causes the person to experience dissociation when they see their body.

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